NEW ARTICLE IN BIOSENSORS FOR INHIBITING AGGREGATION OF COPPER-AMYLOID BETA AGGREGATES
Congratulations to the Nag lab members for developing a bifunctional copper-selective sensor that inhibits the aggregation of toxic non-amyloidogenic amyloid-beta aggregates in the presence of copper! Kudos to Kim Nguyen and Bella Poduska for doing this important work as undergraduate students; this is no small feat! Check out the research article here
CHECK OUT OUR LATEST PUBLICATION ON DEVELOPING A NOVEL CATALYST FOR HETEROGENEOUS CuAAC
Congratulations to the Nag lab members and the Sameera group (University of Colombo) for their successful collaboration and the resulting article on developing a novel cCu(I) catalyst for heterogeneous CuAAC for biomolecule synthesis. Link
CHECK OUT OUR BOOK CHAPTER IN METHODS IN ENZYMOLOGY
We have written a detailed protocol on how to synthesize and sequence the tetrazine-cyclized libraries we have generated, in the highly reputed book series of Methods in Enzymology. Check it out here! chttps://authors.elsevier.com/a/1i%7EVVHRzCT-fn
WELCOME NEW UNDERGRADS!
The Nag lab welcomes new undergraduates, sophomores Ryan, Siobhan, Jovana, Sofi, Zack, and junior Luke!
CONGRATULATIONS ON NEW COMMUNICATIONS CHEMISTRY ARTICLE!
Congratulations to Dr. Nag for her publication in Commun. Chem. article! Read it here
TETRAZINE-CYCLIZED PEPTIDE LIBRARY ARTICLE
Congratulations to Nag lab members for finishing the article on the tetrazine-cyclized peptide library (under review). This was a great group effort involving so many of the members!
WELCOME NEW UNDERGRADS!
The Nag lab welcomes sophomores Ian, Siri, Antonia, and juniors Matt, Malik, Besma, and Kseniia!
WELCOME TO OUR NEW POST-DOCTORAL RESEARCH FELLOW!
The Nag Lab welcomes Dr. Manoranjan Bera. He is a Ph.D. from IIT Kharagpur, India, with a focus on the photochemistry of organic probes. He will be working on the
CONGRATULATIONS TO 2022 GRADUATES AND UNDERGRADUATES!
Congratulations to Persis, Emily, Noa, Kim, Henna, Caroline, and Tamara for completing their degree with flying colors! And congratulations to Chi for getting her successful MS degree completion! We wish them the best of luck in their future endeavors!
CONGRATULATIONS TO THE NAG LAB FOR GETTING FUNDED BY THE NATIONAL SCIENCE FOUNDATION
Our proposal on “ Macrocyclic Peptidomimetic Scaffolds for Sensing of Phosphate-containing Metabolites” has been funded by the NSF LEAPS-MPS (Launching Early-Career Academic Pathways in the Mathematical and Physical Sciences). Read the abstract of the grant here!
READ THE RESEARCH DONE ON CYCLIC PEPTIDE LIGAND DEVELOPMENT AND CELL PENETRATION BY DR. NAG (COLLABORATION CALTECH)
We will submit, ASAP, the extensive work done by Dr. Nag on the development of a macrocyclic ligand for the protein kinase B or Akt2, and the systemic optimization of this ligand to make it cell-penetrant, while retaining its selectivity for Akt. In the meantime, you can read the preprint here!
CHECK OUT THE CHAPTER IN THE METHODS IN MOLECULAR BIOLOGY BOOK THAT WE WROTE!
Congratulations to Ariane Borges, Iryna Onasenko and Dr. Nag on publication of the book Peptide Macrocycles: Methods and Protocols. This book contains very specific protocols for synthesis, characterization and applications of peptide macrocycles. Authors include leading scientists in the field. Link
CONGRATULATIONS TO LAB MEMBERS ARIANE BORGES AND KIM NGYUEN FOR BEING CHOSEN TO ATTEND THE ACS LEADS CONFERENCE 2022
Read the story here!
CONGRATULATIONS TO DR. NAG ON WINNING THE HODGKINS FACULTY AWARD
The Hodgkins Faculty award is given to a Clark University Assistant Professor or an Associate Professor before a first post-tenure review, for outstanding scholarship, research, teaching and community engagement. Dr. Nag received the Hodgkins Faculty award in 2021, along with Prof. Nathan Ahlgreen (Biology) and Dr. Amir Aazami (Mathematics).
NAG LAB MEMBERS SHARE THEIR JOURNEYS AND RESEARCH WITH WORCESTER HIGH SCHOOL STUDENTS
Read the story here!
CHAPTER PUBLISHED IN METHODS IN MOLECULAR BIOLOGY BOOK ON PEPTIDE MACROCYCLES
Congratulations to Ariane Borges, Iryna Onasenko and Dr. Nag for publication of a chapter about qualitative and quantitative cyclic peptide binding assays in a new book titled Peptide Macrocycles -Methods and Protocols in the prestigious book series Methods in Molecular Biology by Springer. Check out the chapter here!
PAPER ACCEPTED IN RSC ADVANCES!
Congratulations to Rene Kandler, Samir Das and Dr. Nag for acceptance of the article “Copper-ligand clusters dictate size of cyclized peptide formed during alkyne-azide cycloaddition on solid support” in RSc. Advances! Read the article here!
PAPER ACCEPTED IN ISRAEL JOURNAL OF CHEMISTRY
Congratulations to Dr. Das and Dr. Nag for acceptance of the article “Fluorescent Sensors of Phosphate Containing Biomolecules” in Israel Journal of Chemistry! Read the article here!
NAG LAB WELCOMES NEW MEMBERS!
The Nag lab welcomes Tamara Allakhverdova and CarolineWang, Juniors in BCMB, and Inonge Kaloustan, a Senior in Psychology, as our newest lab members!
PROVISIONAL PATENT FILED FOR NIH SUPPORTED RESEARCH
Congratulations to Dr. Nag and Dr. Das on filing a provisional patent (Sep 2020) for the NIH supported research in PPI inhibition!
CONGRATULATIONS TO NAG LAB FOR RECEIVING THE NIH R15 GRANT!
Congratulations to the Nag lab for getting the NIH Research Enhancement Award (R15) starting September 2020!
CONGRATULATIONS TO DR. NAG FOR RECEIVING AAUW GRANT!
Congratulations to Dr. Nag for receiving the “Research Publication Grant in Engineering, Medicine and Science, 2020-21” from American Association of University Women.
BOOK CHAPTER IN NEW SPRINGER BOOK “PEPTIDE MACROCYCLES: METHODS AND PROTOCOLS”
Congratulations to Ariane Borges and Iryna Onasenko for authoring with Dr. Nag a chapter “Binding characterization of cyclic peptide ligands to target proteins and chemical epitopes using ELISA and Fluorescence Polarization assays” in the book “Peptide Macrocycles: Methods and Protocols” (Editors Matthew B. Coppock, PhD and Alexander J. Winton, PhD), Springer, forthcoming Nov 2021
INTERNSHIP AT ABBVIE (ONGOING COLLABORATION):
Congratulations to Maddie Letendre for gettting an internship to do summer research at AbbVie, Worcester with Dr. Dhaval Nanavati for de novo sequencing! We are collaborating with AbbVie for sequencing our peptide library!
NAG LAB MEMBERS GET HIGHEST BCMB HONORS:
Congratulations to Iryna Onasenko and Madison Letendre for getting the Highest Honors in BCMB for their undergraduate research!
NEW GROUP MEMBERS 2020:
Nag lab welcomes new members Dillon Prus, Chi Ngyugen, Anastasiia Yerzhova, Tarishi Pathak (Juniors).
PUBLICATION IN SPECIAL ISSUE “EMERGING NEW SCIENTISTS IN NORTH AMERICA” FOR JOURNAL OF SUPRAMOLECULAR CHEMISTRY
Check out our publication in the Journal of Supramolecular Chemistry “Biological applications of amide and amino acid containing synthetic macrocycles” Download
NEW GROUP MEMBERS 2019:
Nag lab welcomes new members Iryna Onasenko, Maddie Letendre, Emma Narkewicz (Juniors) and Kim Le, Anna Livia Jaffe!
2019 NACSETAC MEETING:
Congratulations to Molly and Anny for presenting their research and representing the Nag Lab at the NACSETAC 25th annual meeting!
WPI NEXT-IN-BIO RESEARCH SYMPOSIUM:
Congratulations Dylan and Ailin for representing the Nag lab and doing a great poster presentation at the 2018 WPI Next-In-Bio Symposium !
2018 PUBLICATION:
Please check out the first publication from the Nag lab in the Journal of Medicinal Chemistry and Drug Design at https://www.sciforschenonline.org/journals/medicinal-chemistry-drug-design/JMCDD-1-110.php
Congratulations Anny, Rene and Dylan on acceptance of your manuscript in J. Med. Chem. and Drug. Des.!
2018 NEW STUDENTS:
Nag lab welcomes our newest PhD student, Ariane Borges!
2018 AMERICAN CHEMICAL SOCIETY (ACS) CONFERENCE:
Congratulations Rene for representing the Nag lab and doing a great poster presentation at the 2018 ACS conference!
2018 SUMMER RESEARCH:
Congratulations to Dylan and Molly for completing their Summer research and presenting at the Clark Academic Spree Day!
2018 GRADUATION:
Congratulations to Anny for completing her degree from Biochemistry and Molecular Biology ! We look forward to having her as a Master's student in the lab.
2018 SPRING FEST: Nag lab first poster presentation